Formation of carbohydrate-functionalised polystyrene and glass slides and their analysis by MALDI-TOF MS.
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ABSTRACT:
SUBMITTER: Weissenborn MJ
PROVIDER: S-EPMC3388864 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Formation of carbohydrate-functionalised polystyrene and glass slides and their analysis by MALDI-TOF MS.
Weissenborn Martin J MJ Wehner Johannes W JW Gray Christopher J CJ Sardzík Robert R Eyers Claire E CE Lindhorst Thisbe K TK Flitsch Sabine L SL
Beilstein journal of organic chemistry 20120521
Glycans functionalised with hydrophobic trityl groups were synthesised and adsorbed onto polystyrene and glass slides in an array format. The adsorbed glycans could be analysed directly on these minimally conducting surfaces by MALDI-TOF mass spectrometry analysis after aluminium tape was attached to the underside of the slides. Furthermore, the trityl group appeared to act as an internal matrix and no additional matrix was necessary for the MS analysis. Thus, trityl groups can be used as simple ...[more]
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