Ontology highlight
ABSTRACT:
SUBMITTER: Beckmann HS
PROVIDER: S-EPMC3388869 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Beckmann Henning S G HS Möller Heiko M HM Wittmann Valentin V
Beilstein journal of organic chemistry 20120601
A series of six mono-, di-, and trivalent N,N'-diacetylchitobiose derivatives was conveniently prepared by employing a one-pot procedure for Cu(II)-catalyzed diazo transfer and Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) starting from commercially available amines. These glycoclusters were probed for their binding potencies to the plant lectin wheat germ agglutinin (WGA) from Triticum vulgaris by an enzyme-linked lectin assay (ELLA) employing covalently immobilized N-acetylglucosamine (Gl ...[more]