Ontology highlight
ABSTRACT:
SUBMITTER: Song P
PROVIDER: S-EPMC3389145 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Analytical chemistry 20120524 11
Developing sensors for in vivo chemical monitoring is a daunting challenge. An alternative approach is to couple sampling methods with online analytical techniques; however, such approaches are generally hampered by lower temporal resolution and slow analysis. In this work, microdialysis sampling was coupled with segmented flow electrospray ionization mass spectrometry (ESI-MS) to perform in vivo chemical monitoring. The use of segmented flow to prevent Taylor dispersion of collected zones and r ...[more]