Ontology highlight
ABSTRACT:
SUBMITTER: Tsilidis KK
PROVIDER: S-EPMC3390010 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Tsilidis Konstantinos K KK Travis Ruth C RC Appleby Paul N PN Allen Naomi E NE Lindstrom Sara S Schumacher Fredrick R FR Cox David D Hsing Ann W AW Ma Jing J Severi Gianluca G Albanes Demetrius D Virtamo Jarmo J Boeing Heiner H Bueno-de-Mesquita H Bas HB Johansson Mattias M Quirós J Ramón JR Riboli Elio E Siddiq Afshan A Tjønneland Anne A Trichopoulos Dimitrios D Tumino Rosario R Gaziano J Michael JM Giovannucci Edward E Hunter David J DJ Kraft Peter P Stampfer Meir J MJ Giles Graham G GG Andriole Gerald L GL Berndt Sonja I SI Chanock Stephen J SJ Hayes Richard B RB Key Timothy J TJ
American journal of epidemiology 20120329 9
Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with prostate cancer risk. There is limited information on the mechanistic basis of these associations, particularly about whether they interact with circulating concentrations of growth factors and sex hormones, which may be important in prostate cancer etiology. Using conditional logistic regression, the authors compared per-allele odds ratios for prostate cancer for 39 GWAS-identified ...[more]