Ontology highlight
ABSTRACT:
SUBMITTER: Jacobs AH
PROVIDER: S-EPMC3390799 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Jacobs Andreas H AH Tavitian Bertrand B
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120502 7
Inflammation is a highly dynamic and complex adaptive process to preserve and restore tissue homeostasis. Originally viewed as an immune-privileged organ, the central nervous system (CNS) is now recognized to have a constant interplay with the innate and the adaptive immune systems, where resident microglia and infiltrating immune cells from the periphery have important roles. Common diseases of the CNS, such as stroke, multiple sclerosis (MS), and neurodegeneration, elicit a neuroinflammatory r ...[more]