Ontology highlight
ABSTRACT:
SUBMITTER: Cerami C
PROVIDER: S-EPMC5454906 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Cerami Chiara C Iaccarino Leonardo L Perani Daniela D
International journal of molecular sciences 20170505 5
Neurodegeneration elicits neuroinflammatory responses to kill pathogens, clear debris and support tissue repair. Neuroinflammation is a dynamic biological response characterized by the recruitment of innate and adaptive immune system cells in the site of tissue damage. Resident microglia and infiltrating immune cells partake in the restoration of central nervous system homeostasis. Nevertheless, their activation may shift to chronic and aggressive responses, which jeopardize neuron survival and ...[more]