Ontology highlight
ABSTRACT:
SUBMITTER: Fang R
PROVIDER: S-EPMC3391126 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Fang Rong R Xiao Tian T Fang Zhaoyuan Z Sun Yihua Y Li Fei F Gao Yijun Y Feng Yan Y Li Li L Wang Ye Y Liu Xiaolong X Chen Haiquan H Liu Xin-Yuan XY Ji Hongbin H
The Journal of biological chemistry 20120516 27
High glycolysis, well known as "Warburg effect," is frequently observed in a variety of cancers. Whether the deregulation of miRNAs contributes to the Warburg effect remains largely unknown. Because miRNA regulates gene expression at both mRNA and protein levels, we constructed a gene functional association network, which allows us to detect the gene activity instead of gene expression, to integratively analyze the microarray data for gene expression and miRNA expression profiling and identify g ...[more]