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ABSTRACT:
SUBMITTER: Muroni D
PROVIDER: S-EPMC3394017 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Acta crystallographica. Section E, Structure reports online 20120627 Pt 7
The structure determination confirms the stereochemistry of the title compound, C(21)H(35)NO(3), obtained as an inter-mediate in the enanti-oselective synthesis of de-oxy-nojirimicine analogs. The system contains a pyrrolo-[1,2-a]azocine backbone, which was synthesized by a domino process involving a [2,3]-sigmatropic rearrangement. The incorporation of a chiral auxiliary (-)-menthyl, whose stereocentres are not involved during the synthesis, enables the assignation of absolute configuration. Th ...[more]