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ABSTRACT:
SUBMITTER: Thevenet P
PROVIDER: S-EPMC3394260 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Thévenet Pierre P Shen Yimin Y Maupetit Julien J Guyon Frédéric F Derreumaux Philippe P Tufféry Pierre P
Nucleic acids research 20120511 Web Server issue
In the context of the renewed interest of peptides as therapeutics, it is important to have an on-line resource for 3D structure prediction of peptides with well-defined structures in aqueous solution. We present an updated version of PEP-FOLD allowing the treatment of both linear and disulphide bonded cyclic peptides with 9-36 amino acids. The server makes possible to define disulphide bonds and any residue-residue proximity under the guidance of the biologists. Using a benchmark of 34 cyclic p ...[more]