CSA: comprehensive comparison of pairwise protein structure alignments.

ABSTRACT: CSA is a web server for the computation, evaluation and comprehensive comparison of pairwise protein structure alignments. Its exact alignment engine computes either optimal, top-scoring alignments or heuristic alignments with quality guarantee for the inter-residue distance-based scorings of contact map overlap, PAUL, DALI and MATRAS. These and additional, uploaded alignments are compared using a number of quality measures and intuitive visualizations. CSA brings new insight into the structural relationship of the protein pairs under investigation and is a valuable tool for studying structural similarities. It is available at http://csa.project.cwi.nl.

SUBMITTER: Wohlers I 

PROVIDER: S-EPMC3394275 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature