Ontology highlight
ABSTRACT:
SUBMITTER: Alvarado A
PROVIDER: S-EPMC3394729 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Alvarado Andrés A Garcillán-Barcia M Pilar MP de la Cruz Fernando F
PloS one 20120711 7
Transmissible plasmids are responsible for the spread of genetic determinants, such as antibiotic resistance or virulence traits, causing a large ecological and epidemiological impact. Transmissible plasmids, either conjugative or mobilizable, have in common the presence of a relaxase gene. Relaxases were previously classified in six protein families according to their phylogeny. Degenerate primers hybridizing to coding sequences of conserved amino acid motifs were designed to amplify related re ...[more]