Ontology highlight
ABSTRACT:
SUBMITTER: Cesarini E
PROVIDER: S-EPMC3395664 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Cesarini Elisa E D'Alfonso Anna A Camilloni Giorgio G
Molecular biology of the cell 20120523 14
Transcription-associated recombination is an important process involved in several aspects of cell physiology. In the ribosomal DNA (rDNA) of Saccharomyces cerevisiae, RNA polymerase II transcription-dependent recombination has been demonstrated among the repeated units. In this study, we investigate the mechanisms controlling this process at the chromatin level. On the basis of a small biased screening, we found that mutants of histone deacetylases and chromatin architectural proteins alter bot ...[more]