Ontology highlight
ABSTRACT:
SUBMITTER: Sun J
PROVIDER: S-EPMC3395719 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Sun Jiangwen J Bi Jinbo J Chan Grace G Oslin David D Farrer Lindsay L Gelernter Joel J Kranzler Henry R HR
Addictive behaviors 20120526 10
Although there is evidence that opioid dependence (OD) is heritable, efforts to identify genes contributing to risk for the disorder have been hampered by its complex etiology and variable clinical manifestations. Decomposition of a complex set of opioid users into homogeneous subgroups could enhance genetic analysis. We applied a series of data mining techniques, including multiple correspondence analysis, variable selection and cluster analysis, to 69 opioid-related measures from 5390 subjects ...[more]