Ontology highlight
ABSTRACT:
SUBMITTER: Marcucci L
PROVIDER: S-EPMC3397984 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Marcucci Lorenzo L Yanagida Toshio T
PloS one 20120716 7
Muscular force generation in response to external stimuli is the result of thermally fluctuating, cyclical interactions between myosin and actin, which together form the actomyosin complex. Normally, these fluctuations are modelled using transition rate functions that are based on muscle fiber behaviour, in a phenomenological fashion. However, such a basis reduces the predictive power of these models. As an alternative, we propose a model which uses direct single molecule observations of actomyo ...[more]