Ontology highlight
ABSTRACT:
SUBMITTER: Burnham DR
PROVIDER: S-EPMC4180755 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Burnham Daniel R DR De Vlaminck Iwijn I Henighan Thomas T Dekker Cees C
PloS one 20140929 9
Measurements in magnetic tweezers rely upon precise determination of the position of a magnetic microsphere. Fluctuations in the position due to Brownian motion allows calculation of the applied force, enabling deduction of the force-extension response function for a single DNA molecule that is attached to the microsphere. The standard approach relies upon using the mean of position fluctuations, which is valid when the microsphere axial position fluctuations obey a normal distribution. However, ...[more]