Ontology highlight
ABSTRACT:
SUBMITTER: Page EK
PROVIDER: S-EPMC3399382 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Frontiers in immunology 20120718
Since the concept of immunologic tolerance was discovered in the 1940s, the pursuit of tolerance induction in human transplantation has led to a rapid development of pharmacologic and biologic agents. Short-term graft survival remains an all-time high, but successful withdrawal of immunosuppression to achieve operational tolerance rarely occurs outside of liver transplantation. Collaborative efforts through the NIH sponsored Immune Tolerance Network and the European Commission sponsored Reprogra ...[more]