Ontology highlight
ABSTRACT:
SUBMITTER: Zhuang Q
PROVIDER: S-EPMC7573100 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhuang Quan Q Cai Haozheng H Cao Qingtai Q Li Zixin Z Liu Shu S Ming Yingzi Y
Frontiers in immunology 20201006
Over a half century, organ transplantation has become an effective method for the treatment of end-stage visceral diseases. Although the application of immunosuppressants (IS) minimizes the rate of allograft rejection, the common use of IS bring many adverse effects to transplant patients. Moreover, true transplant tolerance is very rare in clinical practice. Dendritic cells (DCs) are thought to be the most potent antigen-presenting cells, which makes a bridge between innate and adaptive immunit ...[more]