Ontology highlight
ABSTRACT:
SUBMITTER: Chen YB
PROVIDER: S-EPMC3401221 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Chen Yi-Bin YB McDonough Sean S Hasserjian Robert R Chen Heidi H Coughlin Erin E Illiano Christina C Park In Sun IS Jagasia Madan M Spitzer Thomas R TR Cutler Corey S CS Soiffer Robert J RJ Ritz Jerome J
Blood 20120601 3
Acute GVHD (aGVHD) remains a major source of morbidity after allogeneic hematopoietic cell transplantation. CD30 is a cell-surface protein expressed on certain activated T cells. We analyzed CD30 expression on peripheral blood T-cell subsets and soluble CD30 levels in 26 patients at the time of presentation of aGVHD, before the initiation of treatment, compared with 27 patients after hematopoietic cell transplantation without aGVHD (NONE). Analysis by flow cytometry showed that patients with aGV ...[more]