Ontology highlight
ABSTRACT:
SUBMITTER: Buitrago-Perez A
PROVIDER: S-EPMC3402432 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Buitrago-Pérez Águeda Á Hachimi Mariam M Dueñas Marta M Lloveras Belén B Santos Almudena A Holguín Almudena A Duarte Blanca B Santiago Juan Luis JL Akgül Baki B Rodríguez-Peralto José L JL Storey Alan A Ribas Catalina C Larcher Fernando F del Rio Marcela M Paramio Jesús M JM García-Escudero Ramón R
PloS one 20120723 7
Human papillomavirus (HPV) is the causative agent of human cervical cancer and has been associated with oropharyngeal squamous cell carcinoma development. Although prophylactic vaccines have been developed, there is a need to develop new targeted therapies for individuals affected with malignant infected lesions in these locations, which must be tested in appropriate models. Cutaneous beta HPV types appear to be involved in skin carcinogenesis. Virus oncogenicity is partly achieved by inactivati ...[more]