Ontology highlight
ABSTRACT:
SUBMITTER: Huang L
PROVIDER: S-EPMC3403465 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20120329 5
Cold shock proteins (Csps) play an important role in cold shock response of a diverse number of organisms ranging from bacteria to humans. Numerous studies of the Csp from various species showed that a two-state folding mechanism is conserved and the transition state (TS) appears to be very compact. However, the atomic details of the folding mechanism of Csp remain unclear. This study presents the folding mechanism of Csp in atomic detail using an all-atom Go model-based simulations. Our simulat ...[more]