Ontology highlight
ABSTRACT:
SUBMITTER: Al Safadi R
PROVIDER: S-EPMC3405000 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Al Safadi Rim R Abu-Ali Galeb S GS Sloup Rudolph E RE Rudrik James T JT Waters Christopher M CM Eaton Kathryn A KA Manning Shannon D SD
PloS one 20120725 7
The emergence of novel pathogens poses a major public health threat causing widespread epidemics in susceptible populations. The Escherichia coli O104:H4 strain implicated in a 2011 outbreak in northern Germany caused the highest frequency of hemolytic uremic syndrome (HUS) and death ever recorded in a single E. coli outbreak. Therefore, it has been suggested that this strain is more virulent than other pathogenic E. coli (e.g., E. coli O157:H7). The E. coli O104:H4 outbreak strain possesses mul ...[more]