Her versus his migraine: multiple sex differences in brain function and structure.
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ABSTRACT:
SUBMITTER: Maleki N
PROVIDER: S-EPMC3407427 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Publications
Her versus his migraine: multiple sex differences in brain function and structure.
Maleki Nasim N Linnman Clas C Brawn Jennifer J Burstein Rami R Becerra Lino L Borsook David D
Brain : a journal of neurology 20120801 Pt 8
Migraine is twice as common in females as in males, but the mechanisms behind this difference are still poorly understood. We used high-field magnetic resonance imaging in male and female age-matched interictal (migraine free) migraineurs and matched healthy controls to determine alterations in brain structure. Female migraineurs had thicker posterior insula and precuneus cortices compared with male migraineurs and healthy controls of both sexes. Furthermore, evaluation of functional responses t ...[more]
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