Ontology highlight
ABSTRACT:
SUBMITTER: Kumar P
PROVIDER: S-EPMC3408562 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Kumar Praveen P Wittmann Torsten T
Trends in cell biology 20120628 8
+TIPs are a heterogeneous class of proteins that specifically bind to growing microtubule ends. Because dynamic microtubules are essential for many intracellular processes, +TIPs play important roles in regulating microtubule dynamics and microtubule interactions with other intracellular structures. End-binding proteins (EBs) recognize a structural cap at growing microtubule ends, and have emerged as central adaptors that mediate microtubule plus-end tracking of potentially all other +TIPs. The ...[more]