Discovering the bacterial circular proteins: bacteriocins, cyanobactins, and pilins.
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SUBMITTER: Montalban-Lopez M
PROVIDER: S-EPMC3411037 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
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Discovering the bacterial circular proteins: bacteriocins, cyanobactins, and pilins.
Montalbán-López Manuel M Sánchez-Hidalgo Marina M Cebrián Rubén R Maqueda Mercedes M
The Journal of biological chemistry 20120614 32
Over recent years, several examples of natural ribosomally synthesized circular proteins and peptides from diverse organisms have been described. They are a group of proteins for which the precursors must be post-translationally modified to join the N and C termini with a peptide bond. This feature appears to confer a range of potential advantages because these proteins show increased resistance to proteases and higher thermodynamic stability, both of which improve their biological activity. The ...[more]
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