Ontology highlight
ABSTRACT:
SUBMITTER: Karr JR
PROVIDER: S-EPMC3413483 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Cell 20120701 2
Understanding how complex phenotypes arise from individual molecules and their interactions is a primary challenge in biology that computational approaches are poised to tackle. We report a whole-cell computational model of the life cycle of the human pathogen Mycoplasma genitalium that includes all of its molecular components and their interactions. An integrative approach to modeling that combines diverse mathematics enabled the simultaneous inclusion of fundamentally different cellular proces ...[more]