Ontology highlight
ABSTRACT:
SUBMITTER: Hernandez Linares MG
PROVIDER: S-EPMC3414291 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Acta crystallographica. Section E, Structure reports online 20120707 Pt 8
Diosgenone [(20S,22R,25R)-spirost-4-en-3-one, C(27)H(40)O(3)] has been proposed as a new therapeutic alternative for the treatment of malaria. The first X-ray structure report for diosgenone was by Piro et al. [(2002). Z. Naturforsch. Teil C, 57, 947-950] in the space group P2(1) (Z' = 2). We now report a new polymorph in the same space group, with two mol-ecules in the asymmetric unit. Both mol-ecules have similar conformations, characterized by a skewed envelope A ring, which contains the C=C ...[more]