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(3E,5E)-3,5-Bis(4-methyl-benzyl-idene)-1-[3-(piperidin-1-yl)propano-yl]piperidin-4-one.

ABSTRACT: In the title compound, C(29)H(34)N(2)O(2), the central piperidine ring adopts a half-chair conformation, whereas the terminal one adopts a chair conformation. The mean plane of the central piperidine ring [maximum deviation = 0.384 (2) Å] makes dihedral angles of 64.82 (13) and 17.55 (13)° with the benzene rings. In the crystal, mol-ecules are linked into a tape along the b axis via C-H⋯O inter-actions, generating R(2) (2)(20) and R(2) (1)(6) graph-set motifs. C-H⋯π inter-actions are observed between the tapes.

SUBMITTER: Kia Y

PROVIDER: S-EPMC3414948 | biostudies-literature |

REPOSITORIES: biostudies-literature

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(3E,5E)-3,5-Dibenzyl-idene-1-[3-(piperidin-1-yl)propano-yl]piperidin-4-one.

Project description:The asymmetric unit of the title compound, C(27)H(30)N(2)O(2), comprises two independent mol-ecules. The dihedral angles between the phenyl rings in the two mol-ecules are 55.59?(8) and 55.39?(8)°. The piperidine rings adopt chair conformations. The crystal structure is stabilized by weak inter-molecular C-H?O and C-H?N hydrogen bonds. The crystal studied was a non-merohedral twin with a domian ratio of 0.75?(2):0.25?(2).

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Project description:In the title compound, C(22)H(17)Cl(2)NO(2), the asymmetric unit consists of two crystallographically independent mol-ecules and each piperidinone ring adopts an envelope conformation. The dihedral angles between the two chloro-benzene rings are 24.81?(10) and 19.15?(8)° in the two mol-ecules. In the crystal, mol-ecules are connected via weak inter-molecular C-H?O hydrogen bonds forming layers perpendicular to the a axis.

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(3E,5E)-3,5-Bis(2-chloro-benzyl-idene)-1-propyl-piperidin-4-one.

Project description:The title compound, C22H21Cl2NO, is a derivative of mono-carbonyl analogues of curcumin (MACs). The mol-ecule has an E conformation for each of the olefinic bonds. The 1-propyl-piperidin-4-one ring has a distorted chair conformation with the ring N and the C and O atoms of the carbonyl group deviating from the mean plane of the remaining four ring C atoms by 0.682?(2), -0.134?(3) and -0.340?(4)?Å, respectively. The dihedral angle between the benzene rings is 26.5?(1)°. In the crystal, mol-ecules are connected by weak C-H?O and C-H?? inter-actions.

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(3E,5E)-1-Allyl-3,5-bis(4-meth-oxy-benzyl-idene)-piperidin-4-one.

Project description:The piperidine ring in the title compound, C24H25NO3, adopts an envelope conformation with the N atom being the flap atom, and each C=C double bond exhibits an E conformation. In the crystal, C-H⋯O hydrogen bonds link the mol-ecules, forming supramolecular layers that stack along the a axis.

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(3E,5E)-3,5-Bis(4-allyl-oxybenzyl-idene)-1-benzyl-piperidin-4-one.

Project description:In the title compound C(32)H(31)NO(3), the all-yloxy groups on either side of the piperidin-4-one ring are conformationally disordered. The contribution of major and minor components of the allyloxy group at the 3rd position of the ring are 0.576?(4) and 0.424?(4), respectively, and those at the 5th position are 0.885?(3) and 0.115?(3), respectively. The six-membered piperidin-4-one ring adopts a sofa conformation with the benzyl group occupying an equatorial position and the olefinic double bonds possessing an E configuration. Flanking phenyl substituents are stretched out on either side of the six-membered ring. ?-? inter-actions with a centroid-centroid distance of 3.885?(1)?Å give rise to mol-ecular dimers and short C-H?? contacts lead to chains along the c axis.

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(3E,5E)-3,5-Bis(4-hy-droxy-benzyl-idene)oxan-4-one.

Project description:In the title compound, C(19)H(16)O(4), there are two 4-hy-droxy-benzyl substituents on the oxan-4-one (tetra-hydro-pyran-4-one) ring, which exhibits an envelope conformation. The dihedral angles between pyran-one ring and the two benzene rings are 26.69?(9) and 36.01?(9)° while the benzene rings make a dihedral angle of 20.88?(10)°. In the crystal, mol-ecules are linked by inter-molecular O-H?O hydrogen bonds into a supra-molecular three-dimensional twofold inter-penetrating hydrogen-bonded network.

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(3E,5E)-3,5-Bis(4-hy-droxy-3,5-di-methoxy-benzyl-idene)oxan-4-one monohydrate.

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