Ontology highlight
ABSTRACT:
SUBMITTER: Winge DR
PROVIDER: S-EPMC3416190 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
The mitochondrial respiratory chain is organized within an array of supercomplexes that function to minimize the generation of reactive oxygen species (ROS) during electron transfer reactions. Structural models of supercomplexes are now known. Another recent advance is the discovery of non-OXPHOS complex proteins that appear to adhere to and seal the individual respiratory complexes to form stable assemblages that prevent electron leakage. This review highlights recent advances in our understand ...[more]