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Archaeal tetrathionate hydrolase goes viral: secretion of a sulfur metabolism enzyme in the form of virus-like particles.


ABSTRACT: In the course of screening for virus-host systems in extreme thermal environments, we have isolated a strain of the hyperthermophilic archaeaon Acidianus hospitalis producing unusual filamentous particles with a zipper-like appearance. The particles were shown to represent a secreted form of a genuine cellular enzyme, tetrathionate hydrolase, involved in sulfur metabolism.

SUBMITTER: Krupovic M 

PROVIDER: S-EPMC3416430 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

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Archaeal tetrathionate hydrolase goes viral: secretion of a sulfur metabolism enzyme in the form of virus-like particles.

Krupovic Mart M   Peixeiro Nuno N   Bettstetter Marcus M   Rachel Reinhard R   Prangishvili David D  

Applied and environmental microbiology 20120525 15


In the course of screening for virus-host systems in extreme thermal environments, we have isolated a strain of the hyperthermophilic archaeaon Acidianus hospitalis producing unusual filamentous particles with a zipper-like appearance. The particles were shown to represent a secreted form of a genuine cellular enzyme, tetrathionate hydrolase, involved in sulfur metabolism. ...[more]

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