Ontology highlight
ABSTRACT:
SUBMITTER: Kitamura K
PROVIDER: S-EPMC3416769 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Kitamura Kei K Kishi-Itakura Chieko C Tsuboi Takafumi T Sato Shigeharu S Sato Shigeharu S Kita Kiyoshi K Ohta Nobuo N Mizushima Noboru N
PloS one 20120810 8
Autophagy is a membrane-mediated degradation process, which is governed by sequential functions of Atg proteins. Although Atg proteins are highly conserved in eukaryotes, protozoa possess only a partial set of Atg proteins. Nonetheless, almost all protozoa have the complete factors belonging to the Atg8 conjugation system, namely, Atg3, Atg4, Atg7, and Atg8. Here, we report the biochemical properties and subcellular localization of the Atg8 protein of the human malaria parasite Plasmodium falcip ...[more]