Dopamine enhances model-based over model-free choice behavior.
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ABSTRACT:
SUBMITTER: Wunderlich K
PROVIDER: S-EPMC3417237 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
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Dopamine enhances model-based over model-free choice behavior.
Wunderlich Klaus K Smittenaar Peter P Dolan Raymond J RJ
Neuron 20120801 3
Decision making is often considered to arise out of contributions from a model-free habitual system and a model-based goal-directed system. Here, we investigated the effect of a dopamine manipulation on the degree to which either system contributes to instrumental behavior in a two-stage Markov decision task, which has been shown to discriminate model-free from model-based control. We found increased dopamine levels promote model-based over model-free choice. ...[more]
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