Ontology highlight
ABSTRACT:
SUBMITTER: Lenardo MJ
PROVIDER: S-EPMC3417315 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Lenardo Michael J MJ McPhee Christina K CK Yu Li L
Methods in enzymology 20090101
In this chapter we discuss methods to study autophagic cell death. A large body of evidence demonstrates that autophagy is a cell survival mechanism in response to starvation. The role of autophagy in cell death, however, has long been controversial. Recently, molecular approaches have provided direct evidence that autophagy contributes to cell death in certain contexts. We begin this chapter by outlining methods to quantify cell death, for example by assaying for cell viability. Next, we discus ...[more]