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Gold-Catalyzed Regioselective Dimerization of Aliphatic Terminal Alkynes.

ABSTRACT: A gold-catalyzed regioselective homodimerization of aliphatic terminal alkynes is described. Bulky and less Lewis acidic tBuXPhosAuNTf(2) is the preferred catalyst, and the additive, anhydrous NaOAc, substantially facilitates the reaction.

SUBMITTER: Sun S

PROVIDER: S-EPMC3419542 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

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Gold-Catalyzed Regioselective Dimerization of Aliphatic Terminal Alkynes.

Sun Sheng S Kroll Julien J Luo Yingdong Y Zhang Liming L

Synlett : accounts and rapid communications in synthetic organic chemistry 20120101 1

A gold-catalyzed regioselective homodimerization of aliphatic terminal alkynes is described. Bulky and less Lewis acidic tBuXPhosAuNTf(2) is the preferred catalyst, and the additive, anhydrous NaOAc, substantially facilitates the reaction. ...[more]

PMID: 22904604

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