Ontology highlight
ABSTRACT:
SUBMITTER: van Helden SF
PROVIDER: S-EPMC3420873 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
van Helden Suzanne F G SF Anthony Eloise C EC Dee Rob R Hordijk Peter L PL
PloS one 20120816 8
Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regulation of the adhesive and migratory behavior is essential for proper functioning of these cells. Rho GTPases are important regulators of adhesion and migration; however, it is unknown which Rho GTPases are expressed in different myeloid cells. Here, we use a qPCR-based approach to investigate Rho GTPase expression in myeloid cells.We found that the mRNAs encoding Cdc42, RhoQ, Rac1, Rac2, RhoA and ...[more]