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Emergence of metallo-?-lactamase GIM-1 in a clinical isolate of Serratia marcescens.

ABSTRACT: The metallo-?-lactamase GIM-1 (German imipenemase) has been found so far only in clinical isolates of Pseudomonas aeruginosa from Germany. Here we report the detection of bla(GIM-1) in a clinical strain of Serratia marcescens that was isolated from urine, blood, and wound samples over a period of 20 months. The strain was repeatedly isolated from one patient in two German hospitals and an outpatient department located in the region in which all previously described GIM-1-producing P. aeruginosa strains were identified.

SUBMITTER: Rieber H 

PROVIDER: S-EPMC3421846 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature

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Emergence of metallo-β-lactamase GIM-1 in a clinical isolate of Serratia marcescens.

Rieber Heime H   Frontzek Andre A   Pfeifer Yvonne Y  

Antimicrobial agents and chemotherapy 20120618 9

The metallo-β-lactamase GIM-1 (German imipenemase) has been found so far only in clinical isolates of Pseudomonas aeruginosa from Germany. Here we report the detection of bla(GIM-1) in a clinical strain of Serratia marcescens that was isolated from urine, blood, and wound samples over a period of 20 months. The strain was repeatedly isolated from one patient in two German hospitals and an outpatient department located in the region in which all previously described GIM-1-producing P. aeruginosa  ...[more]

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