Ontology highlight
ABSTRACT:
SUBMITTER: Stigliano A
PROVIDER: S-EPMC3425859 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Journal of oncology 20120814
Adrenocortical carcinoma (ACC) is a very rare endocrine tumour, with variable prognosis, depending on tumour stage and time of diagnosis. The overall survival is five years from detection. Radical surgery is considered the therapy of choice in the first stages of ACC. However postoperative disease-free survival at 5 years is only around 30% and recurrence rates are frequent. o,p'DDD (ortho-, para'-, dichloro-, diphenyl-, dichloroethane, or mitotane), an adrenolytic drug with significant toxicity ...[more]