Ontology highlight
ABSTRACT:
SUBMITTER: Stultz BG
PROVIDER: S-EPMC3427764 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Stultz Brian G BG Park Sung Yeon SY Mortin Mark A MA Kennison James A JA Hursh Deborah A DA
Developmental biology 20120721 2
The Drosophila BMP, decapentaplegic (dpp), controls morphogenesis of the ventral adult head through expression limited to the lateral peripodial epithelium of the eye-antennal disc by a 3.5 kb enhancer in the 5' end of the gene. We recovered a 15 bp deletion mutation within this enhancer that identified a homeotic (Hox) response element that is a direct target of labial and the homeotic cofactors homothorax and extradenticle. Expression of labial and homothorax are required for dpp expression in ...[more]