Ontology highlight
ABSTRACT:
SUBMITTER: Xue M
PROVIDER: S-EPMC3431915 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Xue Min M Zhong Xing X Shaposhnik Zory Z Qu Yongquan Y Tamanoi Fuyuhiko F Duan Xiangfeng X Zink Jeffrey I JI
Journal of the American Chemical Society 20110524 23
Porous silicon nanoparticles (PSiNPs) were synthesized by silver-assisted electroless chemical etching of silicon nanowires generated on a silicon wafer. The rod-shaped particles (200-400 nm long and 100-200 nm in diameter) were derivatized with a cyclodextrin-based nanovalve that was closed at the physiological pH of 7.4 but open at pH <6. Release profiles in water and tissue culture media showed that no cargo leaked when the valves were closed and that release occurred immediately after acidif ...[more]