Systematic Degradation Rate Analysis of Surface-Functionalized Porous Silicon Nanoparticles.

ABSTRACT: Porous silicon nanoparticles (pSiNPs) have been utilized within a wide spectrum of biological studies, as well as in chemistry, chemical biology, and biomedical fields. Recently, pSiNPs have been constantly coming under the spotlight, mostly in biomedical applications, due to their advantages, such as controlled-release drug delivery in vivo by hydrolysis-induced degradation, self-reporting property through long life-time photoluminescence, high loading efficiency of substrate into pore, and the homing to specific cells/organ/bacteria by surface functionalization. However, the systematic degradation rate analysis of surface-functionalized pSiNPs in different biological media has not been conducted yet. In this paper, we prepared four different surface-functionalized pSiNPs samples and anal

SUBMITTER: Kang RH 

PROVIDER: S-EPMC6416615 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature