Ontology highlight
ABSTRACT:
SUBMITTER: Petruk S
PROVIDER: S-EPMC3432699 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Petruk Svetlana S Sedkov Yurii Y Johnston Danika M DM Hodgson Jacob W JW Black Kathryn L KL Kovermann Sina K SK Beck Samantha S Canaani Eli E Brock Hugh W HW Mazo Alexander A
Cell 20120823 5
Propagation of gene-expression patterns through the cell cycle requires the existence of an epigenetic mark that re-establishes the chromatin architecture of the parental cell in the daughter cells. We devised assays to determine which potential epigenetic marks associate with epigenetic maintenance elements during DNA replication in Drosophila embryos. Histone H3 trimethylated at lysines 4 or 27 is present during transcription but, surprisingly, is replaced by nonmethylated H3 following DNA rep ...[more]