Ontology highlight
ABSTRACT:
SUBMITTER: Zhuang G
PROVIDER: S-EPMC3433782 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Zhuang Guanglei G Wu Xiumin X Jiang Zhaoshi Z Kasman Ian I Yao Jenny J Guan Yinghui Y Oeh Jason J Modrusan Zora Z Bais Carlos C Sampath Deepak D Ferrara Napoleone N
The EMBO journal 20120706 17
Angiogenesis plays a crucial role during tumorigenesis and much progress has been recently made in elucidating the role of VEGF and other growth factors in the regulation of angiogenesis. Recently, microRNAs (miRNAs) have been shown to modulate a variety of physiogical and pathological processes. We identified a set of differentially expressed miRNAs in microvascular endothelial cells co-cultured with tumour cells. Unexpectedly, most miRNAs were derived from tumour cells, packaged into microvesi ...[more]