Ontology highlight
ABSTRACT:
SUBMITTER: van Gennip M
PROVIDER: S-EPMC3434577 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
van Gennip Maria M Christensen Louise Dahl LD Alhede Morten M Qvortrup Klaus K Jensen Peter Østrup PØ Høiby Niels N Givskov Michael M Bjarnsholt Thomas T
Infection and immunity 20120514 8
Chronic infections with Pseudomonas aeruginosa persist because the bacterium forms biofilms that are tolerant to antibiotic treatment and the host immune response. Scanning electron microscopy and confocal laser scanning microscopy were used to visualize biofilm development in vivo following intraperitoneal inoculation of mice with bacteria growing on hollow silicone tubes, as well as to examine the interaction between these bacteria and the host innate immune response. Wild-type P. aeruginosa d ...[more]