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Post-assembly functionalization of organoplatinum(II) metallacycles via copper-free click chemistry.

ABSTRACT: We describe the use of a strain-promoted copper-free click reaction in the post-self-assembly functionalization of organoplatinum(II) metallacycles. The coordination-driven self-assembly of a 120° cyclooctyne-tethered dipyridyl donor with 60° and 120° di-Pt(II) acceptors forms molecular rhomboids and hexagons bearing cyclooctynes. These species undergo post-self-assembly [3+2] Huisgen cycloaddition with a variety of azides to give functionalized ensembles under mild conditions.

SUBMITTER: Chakrabarty R

PROVIDER: S-EPMC3440528 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature

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Post-assembly functionalization of organoplatinum(II) metallacycles via copper-free click chemistry.

Chakrabarty Rajesh R Stang Peter J PJ

Journal of the American Chemical Society 20120828 36

We describe the use of a strain-promoted copper-free click reaction in the post-self-assembly functionalization of organoplatinum(II) metallacycles. The coordination-driven self-assembly of a 120° cyclooctyne-tethered dipyridyl donor with 60° and 120° di-Pt(II) acceptors forms molecular rhomboids and hexagons bearing cyclooctynes. These species undergo post-self-assembly [3+2] Huisgen cycloaddition with a variety of azides to give functionalized ensembles under mild conditions. ...[more]

PMID: 22917086

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