Ontology highlight
ABSTRACT:
SUBMITTER: Martin ME
PROVIDER: S-EPMC3774834 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Martin Molly E ME Parameswarappa Sharavathi G SG O'Dorisio M Sue MS Pigge F Christopher FC Schultz Michael K MK
Bioorganic & medicinal chemistry letters 20100625 16
Attachment of DOTA to a novel monofluoro-cyclooctyne facilitates bioconjugation to an azide-modified peptide via Cu-free click chemistry. The resulting conjugate was radiolabeled with (111)In to afford a potential targeted molecular imaging agent with high specific activity and an excellent radiochemical purity. ...[more]