Ontology highlight
ABSTRACT:
SUBMITTER: Han SJ
PROVIDER: S-EPMC3443781 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Han Sangyoon J SJ Bielawski Kevin S KS Ting Lucas H LH Rodriguez Marita L ML Sniadecki Nathan J NJ
Biophysical journal 20120801 4
Mechanical cues can influence the manner in which cells generate traction forces and form focal adhesions. The stiffness of a cell's substrate and the available area on which it can spread can influence its generation of traction forces, but to what extent these factors are intertwined is unclear. In this study, we used microcontact printing and micropost arrays to control cell spreading, substrate stiffness, and post density to assess their effect on traction forces and focal adhesions. We find ...[more]