Ontology highlight
ABSTRACT:
SUBMITTER: Sultan Z
PROVIDER: S-EPMC344476 | biostudies-literature | 2004 Feb
REPOSITORIES: biostudies-literature
Sultan Zafar Z Nahar Shamsun S Wretlind Bengt B Lindback Emma E Rahman Motiur M
Journal of clinical microbiology 20040201 2
A mismatch amplification mutation assay (MAMA) was developed for identification of point mutations in quinolone resistance-determining region (QRDR) of gyrA at codons 91 and 95. MAMA PCR was used to detect mutations at codons 91 and 95 of gyrA in 117 Neisseria gonorrhoeae isolates (with ciprofloxacin MICs of 0.004 to >32 microg/ml) from Bangladesh during 1997 to 2001. The QRDR regions of the gyrA genes from 31 randomly selected isolates were sequenced, and the results were compared with those of ...[more]