PAirwise Sequence Comparison (PASC) and its application in the classification of filoviruses.
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ABSTRACT:
SUBMITTER: Bao Y
PROVIDER: S-EPMC3446765 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Publications
PAirwise Sequence Comparison (PASC) and its application in the classification of filoviruses.
Bao Yiming Y Chetvernin Vyacheslav V Tatusova Tatiana T
Viruses 20120820 8
PAirwise Sequence Comparison (PASC) is a tool that uses genome sequence similarity to help with virus classification. The PASC tool at NCBI uses two methods: local alignment based on BLAST and global alignment based on Needleman-Wunsch algorithm. It works for complete genomes of viruses of several families/groups, and for the family of Filoviridae, it currently includes 52 complete genomes available in GenBank. It has been shown that BLAST-based alignment approach works better for filoviruses, a ...[more]
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