Ontology highlight
ABSTRACT:
SUBMITTER: Revikumar A
PROVIDER: S-EPMC3449378 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Revikumar Amjesh A Nair Achuthsankar Sukumaran AS Sundaram Sugunan Vetha SV
Bioinformation 20120803 15
Hepatitis C Virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at a risk of developing significant morbidity and mortality. There is no effective treatment or prevention till date for HCV infection. We describe the computed binding of 10 compounds to the allosteric binding site of RNA dependent RNA polymerase enzyme. These compounds were identified from the ZINC database through virtual screening followed by ADMET evaluatio ...[more]