Detecting motifs and patterns at mobile genetic element insertion site.
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ABSTRACT:
SUBMITTER: Dev BB
PROVIDER: S-EPMC3449389 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Detecting motifs and patterns at mobile genetic element insertion site.
Dev Bhuvan Bhaskar BB Malik Aman A Rawal Kamal K
Bioinformation 20120824 16
Mobile genetic elements (MGEs) occupy major proportion of eukaryotic genomes and are present in significant numbers in prokaryote genomes also. Here we report a new method which extracts a motif at the site of insertion of MGE using tools such as DNA SCANNER. The flanking region of the insertion site is extracted and is analyzed in DNA Scanner for physiochemical properties like protein-interaction measures, energy profiles as well as structural parameters. In case significant signals are observe ...[more]
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