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Complete genome sequences of two Helicobacter pylori bacteriophages isolated from Japanese patients.


ABSTRACT: Helicobacter pylori causes peptic ulcers and gastric cancer, which lead to significantly higher morbidity in Japan than elsewhere in the world. As bacteriophage (phage) and host bacteria coevolve, the study of H. pylori phages is important to extend understanding of the evolution and pathogenesis of H. pylori. Here we report two complete genome sequences of H. pylori phages KHP30 and KHP40, which were released spontaneously from the most pathogenic East Asian-type isolates from Japanese patients.

SUBMITTER: Uchiyama J 

PROVIDER: S-EPMC3457131 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature

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Complete genome sequences of two Helicobacter pylori bacteriophages isolated from Japanese patients.

Uchiyama Jumpei J   Takeuchi Hiroaki H   Kato Shin-ichiro S   Takemura-Uchiyama Iyo I   Ujihara Takako T   Daibata Masanori M   Matsuzaki Shigenobu S  

Journal of virology 20121001 20


Helicobacter pylori causes peptic ulcers and gastric cancer, which lead to significantly higher morbidity in Japan than elsewhere in the world. As bacteriophage (phage) and host bacteria coevolve, the study of H. pylori phages is important to extend understanding of the evolution and pathogenesis of H. pylori. Here we report two complete genome sequences of H. pylori phages KHP30 and KHP40, which were released spontaneously from the most pathogenic East Asian-type isolates from Japanese patients  ...[more]

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